The Daily News – May 12, 2025

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New study may let doctors diagnose you years before symptoms appear.

Source: The Times of London 

Studies: https://www.nature.com/articles/s41586-023-06592-6?domain=nature.com 

Transcript

Medical science is entering a completely new era, one that could lead to highly personalized treatments tailored to individual patients. The focus is shifting from studying genes to analyzing proteins, the molecular machinery behind nearly every function in the body. Now, according to a recent article in the Times of London, a groundbreaking new study in the UK is being hailed as a game changer for how we understand and treat diseases. Researchers have launched one of the most ambitious health projects ever undertaken by analyzing thousands of blood proteins. They hope to unlock new insights into diagnosing, preventing and curing conditions ranging from Alzheimer’s all the way to cancer. According to a doctor who is the lead pharmaceutical collaborator on the project, this is what they have to say. This has the potential to transform healthcare. By the end of this decade, proteins play a vital role in the body helping it function, and in some cases malfunction. The study, which is funded by UK Biobank and supported by 14 pharmaceutical companies, will analyze blood samples from 300,000 volunteers by mapping the role of 5,400 different proteins. Scientists hope to uncover how these molecular building blocks influence disease. Knowing which proteins are linked to specific diseases could lead to earlier diagnosis and more effective treatments. One key breakthrough from the pilot study has been identifying different subtypes of depression. The same doctor explained it this way. Maybe you have a subtype primarily driven by inflammatory proteins, and maybe someone else has a subtype of depression strongly driven by metabolic proteins. This could pave the way for more personalized and targeted treatments. Advances in technology now allow researchers to study proteins on a larger scale. One professor from Queen Mary University of London called the study Game Changing. Adding this, the more we measure the more diseases we can actually study, polycystic ovary syndrome, motor neuron disease, kidney, liver, and bone cancers. For all of those, we will make significant headway. Scientists hope to use protein signatures to identify people at higher risk for colorectal cancer or heart disease, enabling early interventions. The professor summed up the excitement of the scientific community saying he felt like a kid in a candy store. This massive effort is set to revolutionize healthcare, offering hope for earlier detection and better treatments for thousands of conditions. If you found this information useful, don’t forget to like, subscribe, and hit that notification bell for more videos. As always, thanks so much for joining us on The Daily News, and we’ll see you next time.

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